‘Pain Hustlers’: Very Fun But Should Have KO’d Big Pharma

Highly entertaining but somewhat morally bereft. In this time where harmful vaccine prescription runs rampant, holding drug companies accountable is paramount.
‘Pain Hustlers’: Very Fun But Should Have KO’d Big Pharma
(L–R) Pete Brenner (Chris Evans), Dr. Neel (Andy Garcia), and Liza Drake (Emily Blunt), in "Pain Hustlers." Brian Douglas/Netflix
Mark Jackson
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Netflix’s “Pain Hustlers” scored low with critics on “Rotten Tomatoes.” However, my number-one rule of movie inferiority is a film that allows my subconscious to fish out my phone and check the time. “Pain Hustlers” will hold your attention.

I tend to approach film criticism from more of a utilitarian standpoint; more of a “Moneyball,” sabermetrics approach. Does it hold your attention? Yes? Then it’s serviceable entertainment—I don’t care a whole lot about film-school type technique griping. Does it tell a good story? Do you want to run to the bathroom but stay in your seat because you don’t want to miss anything? In this day and age where quality is declining everywhere you look, serviceable entertainment is better than technically-correct-but-boring. Let’s not be too hasty and throw the baby out with the bathwater; a fun watch is a good watch.

(L–R) Eric Paley (Amit Shah), Liza (Emily Blunt), and Pete Brenner (Chris Evans), in "Pain Hustlers." (Brian Douglas/Netflix)
(L–R) Eric Paley (Amit Shah), Liza (Emily Blunt), and Pete Brenner (Chris Evans), in "Pain Hustlers." Brian Douglas/Netflix

That said, one problem is that, while the film’s topic is interesting and the stars (especially Emily Blunt) have charisma, most Netflix movies automatically have a sort of low-rent, low-production-value, and whiff of cheap perfume about them. They’re made for the little screen; they don’t feel like a legit movie.

And ultimately, while I mostly agree with the critics—it’s for different reasons. I found the film entertaining, but, unfortunately, morally bereft. When, according to Harvard’s School of Public Health, as of 2022, more than 600,000 people in the United States and Canada have died from opioid overdoses since 1999, holding drug companies accountable really should have been the primary focus; it needed to be more of an indictment of drug companies’ questionable practices (using the afflictions of real-life people to fund excess and luxury) and American hubris.

What Goes On

Based loosely on Evan Hughes’s “The Hard Sell: Crime and Punishment at an Opioid Startup,” “Pain Hustlers” protagonist, Liza Drake (Emily Blunt), is a broke and divorced single mom with a deadbeat ex-husband. Liza dreams of a better life for herself and her daughter Phoebe (Chloe Coleman) who suffers from seizures, the treatment of which Liza cannot afford.
Liza Drake (Emily Blunt) and her daughter Phoebe (Chloe Coleman), in "Pain Hustlers." (Brian Douglas/Netflix)
Liza Drake (Emily Blunt) and her daughter Phoebe (Chloe Coleman), in "Pain Hustlers." Brian Douglas/Netflix

Recently banished from couch-surfing in her sister’s garage, Liza does a brief stint as a stripper. Her first night onstage, she ignores the pole and cozies up at the bar with one Pete Brenner (Chris Evans).

He’s a heavily New-Yawk-accent-sprewing, snake-oil-y drug rep. After noting how talented Liza is at charming him out of his money (she pegs his job description with a cursory Sherlock Holmesian glance), he immediately offers her a job in his marketing department, at swiftly-tanking Zanna Therapeutics. Falsifying her resume, and knowing that his boss, Dr. Neel (Andy Garcia), won’t be able to look past Liza’s shapely gams, she’s hired immediately.

(L–R) Pete Brenner (Chris Evans), Dr. Neel (Andy Garcia), and Liza Drake (Emily Blunt), in "Pain Hustlers." (Brian Douglas/Netflix)
(L–R) Pete Brenner (Chris Evans), Dr. Neel (Andy Garcia), and Liza Drake (Emily Blunt), in "Pain Hustlers." Brian Douglas/Netflix

What It Is

Zanna Therapeutics is a fictionalized version of Insys Therapeutics, a pharmaceutical company that sold a spray version of Fentanyl, the highly addictive opioid. The company was eventually taken down for lying about the drug’s effects and for paying doctors to promote the product.
Liza Drake (Emily Blunt), and Pete Brenner (Chris Evans), in "Pain Hustlers." (Brian Douglas/Netflix)
Liza Drake (Emily Blunt), and Pete Brenner (Chris Evans), in "Pain Hustlers." Brian Douglas/Netflix
What the film does well, albeit briefly, is show how pharmaceutical companies manipulate the system by doing M.D. reconnaissance and then paying small-town doctors to, basically, become drug pushers, touting their particular drug and delivery system as the painkiller of choice. The physician writes the script based on the company and FDA recommendations. The company reports a protocol that economically enhances its bottom line, but (surprise, surprise) puts patients at risk. Finally, the company leaves everything to the physician and then claims ignorance.

Erin Brockovich

“Pain Hustlers” has much in common with Julia Roberts’s “Erin Brockovich,” in that Pete Brenner and Liza, using Liza as a template, put together a sales team of attractive-but-down-on-their-luck single mom female reps with flexible morals born of desperation. They quickly fall in line, hocking the company’s miracle pain medication, Lonafen, with flash and false promises, which are mostly played for laughs.
Dr. Lydell (Brian d'Arcy James) runs a highly questionable medical practice, in "Pain Hustlers." (Brian Douglas/Netflix)
Dr. Lydell (Brian d'Arcy James) runs a highly questionable medical practice, in "Pain Hustlers." Brian Douglas/Netflix
And so, as mentioned at the outset, in that sense, “Pain Hustlers” is too cutesy for a film that should smack you upside the head, take no prisoners, and ask forgiveness later. The topic is inherently too sad to make a comedy out of. I mean, you can, but then you have to commit and go all out. The right thing to do would be to tell this story so that the audience comes away with some pain as motivation to do some reflection, some looking within, to see how we all participated in this modern tragedy.
Liza Drake's (Emily Blunt) attire becomes quite upscale, in "Pain Hustlers." (Brian Douglas/Netflix)
Liza Drake's (Emily Blunt) attire becomes quite upscale, in "Pain Hustlers." Brian Douglas/Netflix

Instead, it relies on Blunt’s star power to gloss over the gaps, such as Liza appearing largely oblivious to the issues Lonafen causes. Sure, it’s known that drug dealers don’t want to know what’s happening with the product they’re selling, as long as it’s in demand. And while—just like Liza herself—Blunt nearly pulls it off, eventually, the problems catch up to her.

But that bit of contriteness at the end is more like Martha Stewart doing jail time and bouncing back better than ever. What did Martha do? Didn’t pay her taxes or something? Turned a blind eye to taxes? Liza’s turning a blind eye resulted in dead people.

However, “Pain Hustlers” is still quite an entertaining watch.

Movie poster for "Pain Hustlers." (Brian Douglas/Netflix)
Movie poster for "Pain Hustlers." Brian Douglas/Netflix
‘Pain Hustlers’ Director: David Yates Starring: Emily Blunt, Chris Evans, Andy Garcia, Catherine O’Hara, Chloe Coleman MPAA Rating: R Running Time: 2 hours, 2 minutes Release Date: Oct. 27, 2023 Rating: 3 out of 5 stars
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Mark Jackson
Mark Jackson
Film Critic
Mark Jackson is the chief film critic for The Epoch Times. In addition to the world’s number-one storytelling vehicle—film, he enjoys martial arts, weightlifting, motorcycles, vision questing, rock-climbing, qigong, oil painting, and human rights activism. Jackson earned a bachelor's degree in philosophy from Williams College, followed by a classical theater training, and has 20 years’ experience as a New York professional actor, working in theater, commercials, and television daytime dramas. He narrated The Epoch Times audiobook “How the Specter of Communism is Ruling Our World,” which is available on iTunes and Audible. Jackson is a Rotten Tomatoes-approved film critic.
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