New research suggests that daily saunas could help women control their blood sugar better and combat post-menopausal weight gain.
Researchers from the University of Massachusetts Amherst found that older female mice receiving daily 30-minute whole-body heat treatments gained less weight and had better insulin sensitivity than those that didn’t receive treatment.
The findings are noteworthy because menopause increases the risk of obesity and insulin resistance due to lower estrogen levels. The researchers also discovered how the heat therapy works to provide these benefits.
“Compared to men, women have a higher likelihood of being obese or overweight,” Soonkyu Chung, associate professor in the Department of Nutrition at the University of Massachusetts Amherst and research team leader, said in a news release.
“This is especially true after menopause, due to the loss of estrogen in the body. Our study suggests that whole-body heat therapy could serve as an effective, non-invasive solution for managing weight gain and insulin resistance associated with menopause.”
Rong Fan, a doctoral student advised by Ms. Chung, presented the findings on July 1 at NUTRITION 2024, the American Society for Nutrition’s annual meeting—held in Chicago.
Study Details
Researchers removed the ovaries of older female mice to mimic menopause. The mice were then fed a high-fat diet that included 45 percent of calories from fat to promote weight gain—to imitate the Western diet. One group of mice was exposed to 30 minutes of heat therapy daily in an enclosure at 40 C (104 F) for 12 weeks, while another group received no heat treatment.The mice who underwent heat therapy had “significantly reduced lactate dehydrogenase levels, indicating less age-related tissue damage.” The treatment also helped reduce weight gain from the high-fat diet.
Compared to the untreated mice, those who underwent heat therapy had better insulin sensitivity and signaling and less fat buildup in areas like the liver and brown fat. Brown fat is a unique type of fat that enables the body to use more energy.
Mechanism of Action
The researchers looked into how heat therapy works at a molecular level. They discovered that heat activates several processes in the body that help burn fat and use energy more efficiently. A protein called TRPV1 plays a significant role.When TRPV1 is activated by heat, it begins a process where the body uses energy to move calcium ions across cell membranes. This process, called futile calcium cycling, boosts the body’s energy expenditure.
Activating TRPV1 and the calcium cycling also helps burn and break down fats, reducing fat buildup in places like the liver. It also improves how the body uses insulin, which is critical for good metabolic health.