Vaccines: A Historical Perspective and the Path Forward

Learn about the history and next steps for vaccines.
Rohane Hamilton/Shutterstock
By Jingduan Yang, M.D.
Updated:
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Vaccines have long been heralded as one of medicine’s most outstanding achievements. They’ve saved millions of lives and transformed public health. They’ve also sparked debates about safety, ethics, and the appropriate role of government in health decisions.

With Robert F. Kennedy Jr.’s recent nomination for Secretary of the Health and Human Services Department, these debates have gained new urgency. Many label Kennedy as “anti-vaccine,” but this oversimplification misses the mark. His concerns center on the safety, accountability, and transparency of vaccine programs—issues we should all take seriously.

As a physician, I view this moment as an opportunity for thoughtful reflection. What have vaccines achieved? What risks have emerged? How can we approach the future of vaccination in a way that respects individual choice while protecting public health?

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Let’s begin with history.

Roots of Vaccination

The concept of vaccination predates modern medicine. One of the earliest documented practices was variolation, first used in 10th-century China and India. Physicians would powder smallpox scabs and have patients inhale them, aiming to protect against severe disease.

This practice spread to Africa and the Ottoman Empire, where it was refined and eventually brought to Europe.

The modern vaccine era began in 1796 when Edward Jenner demonstrated that exposure to cowpox could protect against smallpox. Jenner’s work marked a turning point in the fight against infectious disease and laid the foundation for modern immunology. His efforts eventually led to the eradication of smallpox in 1980, a feat considered one of humanity’s most significant public health victories.
This history illustrates how human ingenuity can overcome seemingly insurmountable challenges. However, even in those early days, vaccination was not without risks or controversy.

The Impact of Vaccines on Public Health

Vaccines have made extraordinary contributions to public health. Diseases that once devastated populations have been brought under control or eradicated.
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Consider these achievements:
  • Smallpox: Before its eradication, smallpox killed an estimated 300 million people in the 20th century. Global vaccination efforts eliminated the disease.
  • Polio: Once a leading cause of paralysis and death, polio is now nearly eradicated worldwide thanks to vaccination campaigns.
  • Measles: Measles is a highly contagious airborne disease caused by a virus that can lead to severe complications and death. According to the World Health Organization (WHO), measles vaccination averted more than 60 million deaths between 2000 and 2023. Even though a safe and cost-effective vaccine is available, in 2023, there were an estimated 107,500 measles deaths globally, mostly among unvaccinated or under-vaccinated children under the age of 5. In 2023, 83 percent of children received a first dose of measles vaccine, well below the 2019 level of 86 percent, states the WHO.

The Risks and Controversies of Vaccination

Despite their benefits, vaccines have risks. Most adverse effects are mild, such as fever or swelling at the injection site, but serious side effects, while rare, do occur.
The Cutter Incident of 1955 remains a sobering reminder of what can go wrong. In this case, an improperly inactivated polio vaccine caused paralytic polio in hundreds of children and led to several deaths. This tragedy underscored the importance of rigorous quality control and safety monitoring.
More recently, concerns have been raised about the rare occurrence of myocarditis following mRNA COVID-19 vaccines, particularly in young males. A study in the New England Journal of Medicine found that while the risk is low, taking the vaccine warrants careful consideration, especially for individuals not at high risk from COVID-19.
Transparency about these risks is essential for maintaining public trust. By acknowledging the risks alongside the benefits, we can foster informed decision-making and preserve the integrity of public health programs.

The Case for Individualized Vaccination

Here’s where the conversation gets even more interesting: Should vaccines follow a one-size-fits-all model?
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We know that individuals respond differently to vaccines. Genetics, age, and underlying health conditions influence immune responses. Research has shown that genetic variations can affect vaccine efficacy and side effects.

In traditional Chinese medicine (TCM), we’ve long recognized that no two individuals are the same. Treatments are tailored to each person’s unique constitution, and this principle could also inform the future of vaccination.

Modern medicine is already moving toward personalized approaches in oncology and pharmacology. Why not extend this concept to vaccines? Imagine a future where vaccination plans are tailored to individual needs, balancing safety and efficacy for everyone.

Moving Forward

Vaccines have undoubtedly changed the course of human history, saving millions of lives and reducing the disease burden worldwide. However, progress requires vigilance, accountability, and respect for individual freedom.

Kennedy has been a polarizing figure in this conversation. His critics argue that his vocal skepticism of vaccine safety measures undermines public trust in vaccination programs, potentially endangering public health. Some believe Kennedy’s advocacy could discourage vaccination, leading to the resurgence of preventable diseases such as measles or polio.

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So why does Kennedy challenge the current system? He focuses on ensuring vaccine safety through rigorous oversight and holding pharmaceutical companies and government agencies accountable for their actions. For example, Kennedy advocates the following:
  • Transparency in Research and Development: Kennedy has repeatedly called for more robust and transparent clinical trials for vaccines, highlighting instances where safety testing may have been rushed or incomplete, such as during the accelerated COVID-19 vaccine rollouts. He advocates making raw trial data publicly available to build trust in vaccine safety and efficacy.
  • Bolstering Oversight Bodies: Kennedy has criticized the close financial ties between pharmaceutical companies and regulatory agencies like the U.S. Centers for Disease Control and Prevention (CDC) and the U.S. Food and Drug Administration (FDA). He argues that these relationships can lead to conflicts of interest, reducing the rigor of safety evaluations. By promoting reforms that separate industry funding from regulatory oversight, Kennedy hopes to restore public confidence.
  • Liability for Pharmaceutical Companies: The National Childhood Vaccine Injury Act of 1986 shields vaccine manufacturers from liability in many cases. Kennedy has called for revisiting these protections, arguing that manufacturers should be held accountable for any harm caused by their products. Accountability, he suggests, will incentivize companies to prioritize safety.
  • Advocating for Informed Consent: Kennedy emphasizes the importance of individuals having access to complete information about the benefits and risks of vaccines before making a decision. He has supported legislation to prevent vaccine mandates, arguing that they infringe on personal freedoms and ethical principles of medical autonomy.

Balancing Public Health and Individual Freedom

Critics may view Kennedy’s advocacy as a threat to public health, especially in an era where misinformation can quickly spread online. However, his focus on accountability doesn’t have to conflict with public health goals. Instead, it can complement them by fostering greater trust and cooperation between individuals and health authorities.
Here’s how public health can work hand in hand with Kennedy’s principles:
  • Improve Public Communication: Public health agencies must adopt a transparent and respectful approach to addressing vaccine concerns. This means openly acknowledging the risks of vaccines, however small, and providing clear, evidence-based answers to questions. Trust is built not by dismissing skepticism but by addressing it directly.
  • Integrate Individualized Medicine: Public health systems should embrace advances in personalized medicine, including vaccine protocols tailored to an individual’s genetic, environmental, and health profile. This approach respects individual differences while maintaining herd immunity.
  • Facilitate Accountability and Oversight: Strengthening regulatory agencies’ independence can ensure that vaccine safety and efficacy remain a top priority. These agencies can regain public trust by reducing conflicts of interest and enhancing transparency.
  • Balance Freedom With Responsibility: Public health programs must balance protecting community health and respecting personal choice. Encouraging voluntary vaccination through education and incentives rather than mandates can achieve widespread immunization while preserving individual liberties.

A Transformative Vision

Kennedy’s calls for accountability offer an opportunity to reimagine how public health operates in a free society. By addressing legitimate concerns about safety and oversight, we can create a system that respects individual freedoms while protecting the health of entire populations.

The future of public health lies in collaboration—between individuals, communities, and governing bodies. This collaboration requires honesty, accountability, and mutual respect. If we can navigate these challenges with care and integrity, we’ll preserve the successes of vaccination and build a more robust, more resilient public health system for future generations.

Views expressed in this article are the opinions of the author and do not necessarily reflect the views of The Epoch Times. Epoch Health welcomes professional discussion and friendly debate. To submit an opinion piece, please follow these guidelines and submit through our form here.
Jingduan Yang
Jingduan Yang
M.D.
Dr. Jingduan Yang, FAPA, is a board-certified psychiatrist specializing in integrative and traditional Chinese medicine for chronic mental, behavioral, and physical illnesses. Dr. Yang is also the founder and medical director of the Yang Institute of Integrative Medicine and the American Institute of Clinical Acupuncture and the CEO of Northern Medical Center in New York state. He contributed to the books "Integrative Psychiatry," "Medicine Matters," and "Integrative Therapies for Cancer." He also co-authored "Facing East: Ancient Secrets for Beauty+Health for Modern Age" by HarperCollins and "Clinical Acupuncture and Ancient Chinese Medicine" by Oxford Press.