The School of Engineering of the University of Hong Kong announced on Oct. 27 that a team led by Dr. Zhiqin Chu from the Department of Electrical and Electronic Engineering and Dr. Lin Yuan from the Department of Mechanical Engineering proposed a new method using single nitrogen-vacancy (NV) centres in nanodiamonds (NDs) to propose a linear polarization modulation (LPM) method which can measure both, the rotational and translational movement of markers on cell substrates.
The highlight of the study is the ability to indicate the translational and rotational motion of markers with high precision. It is a new tool to analyze mechanical interactions at the cell-matrix interface.
Dr. Zhiqin Chu, who is in charge of the research, said that the results have great potential for clinical application, which can help understand some diseases, such as the growth, development, and spread of cancer cells, and the results can be used for early detection, diagnosis, and treatment of cancer.
The research team is working on new methods to further improve optical imaging capabilities and simultaneously map multiple nanodiamonds.
