Anglade told reporters today she is also resigning as member for the Montreal riding of St-Henri—Ste-Anne, effective Dec. 1.
Her leadership had been under pressure since the party elected just 21 members in the Oct. 3 election—down from 31 in the 2018 vote.
The party maintained official Opposition status but saw its share of the popular vote drop to less than 15 per cent, receiving fewer votes than Québec solidaire and the Parti Québécois.
Internal conflict erupted shortly after the election, when Anglade ejected Marie-Claude Nichols from caucus after a disagreement over shadow cabinet roles.
Anglade reversed position shortly after, but Nichols refused to return and said the Liberal leader was unable to properly lead the party.