The Calgary Fire Department said that the force of the explosion created “a large debris field” and several fires.
Many of the injured were believed to have been inside the home when it blew up and were sent to various hospitals in the city, the department said.
Adam Loria, a spokesman for Calgary Emergency Medical Services, said all the people sent to hospital are adults.
He said six people were in life-threatening condition and four received serious injuries.
Loria said there were no children involved and the explosion was in a single-family home.
“It was quite the group effort, not only with EMS, to ensure all patients were cared for and transported in a timely fashion, but as well with our first responder partners Calgary police and Calgary fire,” Loria said.
“They felt the house rock and they came out and took a video right away,” he said.
“It’s nuts to see the house gone. And to see the roof on the other, across the street in the neighbour’s yard.”
Fire and police are on scene trying to determine the cause of the blast.