An elderly couple and another woman were killed after an overnight tornado slammed the town of Golden City, Missouri.
Photos taken of the area showed that much of the town of about 700 was destroyed by the twister.
Video footage posted on YouTube showed a number of buildings that were damaged or destroyed.
Tornadoes also touched down near Joplin, Missouri, where a massive tornado killed 161 people on May 22, 2011.
Carl Junction, located near Golden City, was also hit by a tornado, officials told KMOV.
Aerial photos taken of Jefferson City, Missouri, show the aftermath of a devastating tornado that slammed the city night.
A tornado hit the city, the capital of Missouri, as people were in bed on May 22. Dozens of tornadoes hit other cities in Missouri.
The National Weather Service said it had received 22 reports of tornadoes by late Wednesday, although some of those could be duplicate reporting of the same twister.
A fourth weather-related death may have occurred in Oklahoma, where the Highway Patrol said a woman apparently drowned after driving around a barricade Tuesday near Perkins, about 45 miles northeast of Oklahoma City. The unidentified woman’s body was sent to the state medical examiner’s office to confirm the cause of death. Oklahoma Department of Emergency Management spokeswoman Keli Cain said she isn’t yet listed as what would be the state’s first storm-related death.