However, in all countries and regions around the world, there are people who elect not to receive the COVID-19 vaccines for various reasons. They are a naturally occurring control group, as opposed to the vaccinated population (i.e. the experimental group). Indeed, the whole COVID-19 vaccine campaigns can be regarded as the unprecedented largest human clinical trials on vaccine safety, by design or not, as the vaccines’ long term safety data was not available when they were provided to people under EUA. Then, the unvaccinated population in different parts of the world are very unique large control groups in such a global clinical trial.
Due to the highly valuable health data of this unvaccinated population, between October 2021 and February 2022, a UK-based organization called Control Group Cooperative (CGC) independently collected their self-reported data on their health status, reasons for declining to receive the COVID-19 vaccines, whether they have been infected by the SARS-CoV-2 virus, the severity of their symptoms for the ones that did get infected, and whether they’ve been subject to discrimination or victimization.
What Is the Control Group Cooperative?
The Control Group Cooperative was founded in July 2021 to defend people’s inalienable rights to freedom of choice and bodily integrity. Actually, one of the core principles in public health is the respect of autonomy. The group is particularly concerned with the marginalization and stigmatization of COVID-19 unvaccinated communities around the world. The stakeholders of the cooperative believe that they are making a positive contribution to society by collecting health data from both the SARS-CoV-2 vaccinated and the unvaccinated to facilitate a truly comparative analysis.Their rationale is that there is no existing official control group designated by the governments or health authorities. However, since all the existing COVID-19 vaccines are experimental, and a true scientific experiment (i.e. a controlled experiment) requires at least one group (i.e. the control group) that doesn’t receive the experimental treatment, then the COVID-19 vaccine treatments must have a control group as well in order to properly evaluate their long-term efficacy and safety.
As of now, over 305,000 participants who have voluntarily elected to not be inoculated with COVID-19 vaccines, from over 175 countries have signed up to become part of the control group.
By joining the control group, the participants receive an ID card, which indicates that they “must not be vaccinated” due to their participation. The CGC stated on its website that this ID card is “not an official or legal exemption in any country.” Although these ID cards aren’t recognized by any authorities, many participants have reported that they had helped them avoid vaccination without informed consent, supported their position, and facilitated discussion with others.
Findings of an Independent Analysis of the CGC Survey
When joining the CGC’s control group, the participants agree to fill out a monthly survey about their health status.The aforementioned analysis was performed by a multinational team of independent researchers on the data collected from a cohort over a five month period from October 2021 to February 2022.
Geographic Distribution of the Unvaccinated Communities
Age Group and Gender
Top Reasons for Not Receiving COVID-19 Vaccines
According to the survey, the five leading reasons behind the cohort’s decision to not receive COVID-19 vaccines include preference for natural medicine interventions, distrust of pharmaceutical interventions, distrust of government information on the vaccines, poor or limited trial study data, and fear of long-term side effects. They were of nearly equal importance. Each respondent could select more than one reason that he/she considered equally important.
From the results, we can see that the participants were not refusing medical treatment, nor were they not caring of their own health, as sometimes portrayed by the media and/or authorities. To these unvaccinated people, they just did not think that there is only one way (the vaccine way) to help them medically, and they have been reasonably conservative in taking new vaccine products. No scientist in the world can claim that we understand every aspect of the new vaccine products.
Physical and Mental Health Status of the Unvaccinated Cohort
1) COVID-19 infection before survey
2) COVID-19 infection during five month period
During the five month period from October 2021 through February 2022, in most parts of the world, the highly transmissible Omicron variant became the most prevalent strain, replacing the previously dominant Delta variant. As a result, many people became infected.
3) Severe illness situation of the infected respondents
Given that society had found no way to stop the spread of the Omicron variant, many were infected during this time period—this included many asymptomatic infections. Therefore, our main concern is with the respondents of the cohort who were seriously ill and/or hospitalized.
Fortunately, in the vast majority of the cases, the patients’ symptoms were mild and moderate. The rate of severe illness appeared to be very low (around 2 percent of all respondents). Only 74 individuals among the 5,196 (1.4 percent) confirmed or suspected infected respondents reported that they were hospitalized. This percentage might not be very accurate, as people who are very sick or hospitalized might not be healthy enough or willing to participate in this kind of survey. So, objectively, this kind of survey will have data skewing towards more healthy targets.
Nevertheless, the data here still indicates that this group of unvaccinated people were not more prone to the infection by Omicron, even though they were not protected by the vaccines. Otherwise, the percentage of infection and hospitalization rates among this group of people would be much higher. Therefore, this is a very important piece of data, as well as the core observation in this study.
However, in the above graph, there are no data on the number of deaths, as the deceased wouldn’t be able to self-report their cases. Since it’s simply impossible to know the number of deaths with the survey design, some may criticize the findings as not authoritative, because these cases were not confirmed by doctors. Nevertheless, judging from the small portion of patients with severe illness among the infected cohorts in this group, it is fair to estimate that disease progression upon Omicron infection does not correlate with the vaccination status.
Self-administration of Vitamins and Medicines
Mask-wearing Situation of Infected Respondents
The fact that these participants were not vaccinated doesn’t imply that they were not concerned about their own health or others’ health. In reality, many of them were very conscious of their health and personal hygiene practices to stop the spread of COVID-19.
Discrimination Faced by Unvaccinated Control Group
Some media personnel, authority figures, and government agencies have asserted that the unvaccinated pose a risk to the vaccinated individuals. In November 2021, Professor Gunter Kampf explained in his article published in The Lancet that even vaccinated individuals would continue to spread the SARS-CoV-2 virus. Therefore, the stigmatization of the unvaccinated people cannot be justified scientifically.Job Losses for Participants of Working Age
For the purpose of the survey, people aged 20 to 69 years old were considered of the working age. The highest rates of job losses were reported in Oceania (29 percent of working-age respondents), North America (13 percent), Southern Europe (13 percent), and Southeast Asia (12 percent). Although the report didn’t indicate whether the job losses could be entirely attributed to the vaccine mandates, it’s quite possible that some people would lose jobs due to their refusal to receive the COVID-19 vaccines.Mental Health Status of the Unvaccinated Cohort
Also, although the majority of the unvaccinated respondents didn’t suffer from infection/severe illness, would the stress from vaccine mandates/requirements hurt them psychologically?Their mental health status was self-assessed. Only 12 percent of the participants believed “life is great” during the 5-month period, while around 20 percent of respondents in all age groups were suffering from sustained discouragement and feeling that there’s no hope. Therefore, based on the statistics, a significant proportion of the participants were suffering from emotional distress.
This is also a very noteworthy issue, although the study did not show that mental stress was only caused by discrimination. Anyone who has been subjected to restrictions from all aspects of life, discrimination, and/or even hostility from others for a long period of time can suffer a great deal of mental stress.
In summary, this study provides the unique data about the unvaccinated “control group” under the global gigantic experiment to mass vaccinate the population with newly developed vaccines with new technologies.
It also provides an important reference for public health practitioners to evaluate the policy decision making process in terms of the impacts of certain policies to different communities. For instance, in public health emergencies, there are often dilemmas in terms of public health ethics considerations. But we still need to ask: Are we sticking to “do no harm” ethical standards?