On Friday, Sept. 8, 2023, a gorgeous late summer day in Wisconsin, Dale Niggemann came home and saw a note left on the door by Maggie Stern, 55, his best friend and partner for the past five years.
The note said, “Call 911.” First responders arrived at their home and discovered Ms. Stern’s body.
“She said she was in a lot of pain all the time,” said Mr. Niggemann, 57, who was at Ms. Stern’s side as she struggled with the adverse effects of an antidepressant—and painful withdrawal symptoms each time she tried to wean off them.
“She suffered from migraine headaches, tremors, burning pain sensations in her nerves, and dark thoughts about demons and hell.“ Mr. Niggemann said Maggie knew she had everything to live for, but the pain, caused by the effects of the medication, was too intense. ”Her teeth were grinding down, her toes were curled. That is what these antidepressants do.”
Overprescribed and Growing
More than 1 in 8 Americans take antidepressants, according to the Centers for Disease Control and Prevention and the number likely increased during the pandemic, according to limited research. Many people take antidepressants for off-label uses or uses other than for depression, including anxiety and trouble sleeping.
Seeking Relief Leads to Suffering
About 20 years ago, Ms. Stern was prescribed the SSRI Zoloft (generic name sertraline) after complaining to a doctor of anxiety as she prepared to move from Wisconsin to Alaska to start a new chapter of her life.Mr. Niggemann said her doctor told her it was a “brain vitamin.” Ms. Stern told him that the doctor did not inform her of possible adverse effects.
“If you read this journal, you will have an idea how hard I worked/tried to survive. ”The Pharma crap killed my body, but not my spirit. “I’m still me. But the PAIN is too much to endure. “Please educate/ADVOCATE against All Pharma Drugs, especially vaccines & ‘antidepressants.’”Although the suicides of people who use antidepressant drugs are often blamed on their depression, a rising chorus of family members and physicians say the drugs themselves can lead to suicide as well as violent behavior, agitation, and depression.
Physician Alleges Drug Studies Misreported Suicide Risks
Dr. Peter C. Gøtzsche, an internal medicine physician based in Denmark and author of the book, “Deadly Psychiatry and Organised Denial,” is a leading critic of antidepressant drugs. He published an open letter (pdf) in August 2023 to two prominent medical journals, calling for “retraction of three fraudulent trial reports of antidepressants in children and adolescents.”In the letter, he alleges that “the trial reports seriously underreported suicide attempts, other suicidal events, and precursors to suicide and violence on active drug, and exaggerated the benefits of the drugs substantially.”
Drs. Gøtzsche and Healy said the studies, which included 96 and 219 participants respectively, “appear to have been misreported.” Suicidal events that occurred during the trials were missing from the studies’ publications and reports. “Precursors to suicidality or violence occurred more often on fluoxetine than on placebo,” they said, and, “Patient ratings did not find fluoxetine effective.”
The participants were divided into two groups of 48. One group took fluoxetine, the other group took a placebo.
However, Dr. Gøtzsche noted in his review of the original trial document that one of the 10 young patients treated with fluoxetine was severely harmed and patients in the trial suffered from symptoms including mania, agitation, hyperactivity, physical aggression, and personality disorder.
“Fluoxetine was approved even though a statistical review for the FDA [U.S. Food and Drug Administration] had noted there was not a statistically significant benefit for the drug on the primary outcome in either trial,” Dr. Gøtzsche said in his letter. “Fluoxetine (Prozac) paved the way for the approval of other antidepressants in children and adolescents, and these were the two pivotal placebo-controlled trials in depression.
Further Examinations
Researchers examining the original trial report found it misreported suicide-related events as “emotional lability.” Lability is the quality of being unstable or liable to lapse. The trial report said five patients had suicidal or self-harming behavior while using the drug, but the independent researchers found 11 patients in this category—more than twice the reported number. In their report, published in the BMJ in 2015, researchers concluded that “Neither paroxetine nor high dose imipramine [another antidepressant] showed efficacy for major depression in adolescents, and there was an increase in harms with both drugs.”The BMJ report found that the original paroxetine clinical study report said five patients exhibited suicidal or self-injurious behaviors, but the independent researchers found 11 patients in this category. The clinical study report by SmithKline Beecham, maker of paroxetine, had mostly misreported suicide-related events as “emotional lability.”
Mary K. Billingsley, managing editor of JAACAP, was a recipient of Dr. Gøtzsche’s letter. In an email to The Epoch Times, Ms. Billingsley wrote that the journal will pursue any allegations of misconduct. “Suspected misconduct and/or allegations of academic dishonesty” will be managed according to guidance from an ethics committee, the email said. The editor of JAMA Psychiatry, the other letter recipient, has not responded to a request for comment.
Suicides Among Young People
Impulsive suicides are more likely among younger people, a 2013 study found.Among the signees was Mathy Downing, mother of 12-year-old Candace Leigh Downing. Candace was experiencing frustrations with tests and homework when she entered middle school, so she was taken to see a child psychiatrist. Although she was not depressed and had many friends, she was prescribed Zoloft.
Kim Witczak, whose husband, Woody Witczak, 37, hanged himself five weeks after he began taking Zoloft, also signed the letter.
“Woody wasn’t depressed—he had no history of depression or any other mental illness,” Mrs. Witczak told Epoch Times. “He had just started a new job, and was having trouble sleeping, so he went to his doctor. He was given Zoloft, and the doctor told him it would help him to sleep. Five weeks later Woody took his life. We never questioned the drug. It was given by our doctor, was FDA approved.”
“At the time of Woody’s death, there were no black box suicide warnings on antidepressants.” Mrs. Witczak added.
Mrs. Witczak lobbied Congress and the FDA to implement these warnings, which took effect for children and teens in 2004 and were expanded two years later to include young adults, for 36 different antidepressant drugs. Black box warnings, published on the inserts in prescription boxes, state there is a risk of suicidal thinking and behavior for users under 25 years of age.
Depression’s Controversial ‘Mechanism’
For the past 60 years, Dr. Peter Breggin, a psychiatrist with a psychotherapy practice in Ithaca, N.Y., has been sounding the alarm on the risks of psychiatric drugs. He has written more than 20 books, many co-authored with his wife, journalist Ginger Breggin—about half of which include warnings about the adverse effects of antidepressants. Books authored by Dr. Breggin, who has been called the “conscience of psychiatry,” include “Toxic Psychiatry,” “Medication Madness,” and “Talking Back To Prozac.”
Zoloft, Prozac, and Paxil are classified as selective serotonin reuptake inhibitors (SSRIs). In an interview with The Epoch Times, Dr. Breggin said doctors have made unsubstantiated claims that the inhibition of reuptake of serotonin alleviates depression. As neurotransmitters carry messages between nerves, the reuptake mechanism returns some of them to the nerves where they were created.
“This inhibition of reuptake will allegedly help depression by increasing serotonin in the synapses,” Dr. Breggin said.
This is the explanation psychiatrists give patients but many scientists have long doubted the overly simple explanation that serotonin could be responsible for depression, sadness, apathy, and other things linked to depression.
When this class of antidepressants was originally marketed, psychiatrists claimed they now had a gold standard to treat people because they were going to affect a particular chemical imbalance in their brains in an effective way, Dr. Breggin said.
“And everybody bought it, even though the idea that depression would be linked to one function of the brain was flawed,” Dr. Breggin said. “What anyone would have known, if they hadn’t been influenced by the drug companies, is that you can’t affect one neurotransmitter in the brain by itself because they all are connected. That is why we humans are so complicated.”
Australian researchers, Dr. Wayne D. Hall, then professor of public health policy at University of Queensland, and Dr. Jayne Lucke, senior research fellow at the university, found that recent randomized controlled studies of SSRI antidepressants “increased suicidal ideation early in treatment compared to placebo. Observational studies have found an increased risk of self-harm within 9 days of an antidepressant drug being prescribed.”
They concluded, “If SSRIs increase suicide risk in some patients, the number of additional deaths is very small because ecological studies have generally found that suicide mortality has declined (or at least not increased) as SSRI use has increased.”
Pain in Plain Sight
Army Sgt. Angela Peacock, then 24, was serving in Iraq when a fellow soldier was almost killed by an improvised explosive device. Sgt. Peacock was physically ill at that time, and not with her unit when the convoy was hit. Thoughts of death led her to see an Army psychiatrist, who prescribed a sedative and anti-anxiety drug. The drugs made her feel worse, and she was medically discharged from the service.A few years later, Ms. Peacock was on 18 medications at the same time, including antidepressants. She was having suicidal thoughts, as well as thoughts about possibly killing students in her niece’s school.
“My original problem was compounded by the drugs,” Ms. Peacock told The Epoch Times. “I was put on more than 40 drugs during 13 years to treat the mental health symptoms and side effects. I didn’t realize it was the meds that were keeping me in these bad states until way later.”
Mary Neal Vieten, a board-certified clinical psychologist, is the director of Warfighter Advance, a group that assists warfighters in reintegration after their war experiences. Since 2010, she has treated many people suffering from severe adverse effects of antidepressant drugs. A 22-year Navy veteran, Dr. Vieten was featured alongside Ms. Peacock in the documentary.
She went along with the biochemical model of mental health treatment for the first years of her military career. “It took so many suicides before I asked myself, ‘What are we doing wrong?’” Dr. Vieten said in an interview with The Epoch Times. “I realized that a lot of what I was fed in graduate school was provided by parties that were not impartial, like pharmaceutical companies. Hiding in plain sight was the fact that people getting on antidepressants and killing themselves was a very common outcome.”
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