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They were both accused of failing to order chemicals added to the water to coat the pipes and prevent them from releasing lead.
Flint utilities administrator Michael Glasgow also was charged Wednesday with tampering with evidence for allegedly falsifying lead water-testing results and with willful neglect of duty.
The three could not immediately be reached for comment. It wasn’t known if they have lawyers.
Busch is on paid leave. Prysby recently took another job in the agency.
“They failed Michigan families. Indeed, they failed us all,” Schuette said. “I don’t care where you live.”